Let's face it: The San Francisco liberal that conservatives love to hate is perhaps the biggest loser of the 2010.
Nancy Pelosi was the face of Democratic defeat in 2010.
The former House speaker's fall was perhaps the steepest among Washington politicians. After declaring victory on health care reform earlier in 2010, the first female speaker was forced to give up the gavel after a brutal election in which her name was used by Republicans to tarnish and bring down other Democratic candidates.
Pelosi's next role as minority didn't have quite the same ring to it as House speaker.