1. Home
  2. News & Issues
  3. US Government Info
Gambling, Drugs and Munchies
Effects on the brain are the same, NIH researchers say
 Join the Discussion
"The first drug people try tends to be pot. So all your crack heads have probably smoked pot."
BEANSJW
Read or Reply

  Related Resources
Drugs to Block Cocaine High
High Court Upholds Medicinal Marijuana Ban
• Traffic: The Real Drug Deal
Medicinal Marijuana in Court
 
 From Other Guides
• Cocaine Slang: Parental Awareness
• Cocaine & Crack
• Withdrawal
• Cocaine During Pregnancy
Cocaine & Heart Disease
About Serotonin & Dopamine
Downey Busted - Fired
 
 Elsewhere on the Web
• Institute on Drug Abuse
• Office of National Drug Control Policy
Cocaine Facts and Stats
Drug Abuse Sciences
 

The brains of gamblers respond similarly to the brains of lab animals after being given euphoria-inducing drugs or when being tempted by good food, according to the National Institutes of Health (NIH).

Results of tests conducted by researchers at the Massachusetts General Hospital (MGH) and two other institutions suggest that the same mental circuitry is involved in the highs and lows of winning money, abusing drugs, or anticipating a tasty meal.

Using functional magnetic resonance imaging (fMRI), researchers mapped the neural responses of 12 male subjects while they played a simple game of chance in which they could either win or lose money.  Each subject was give a $50 stake and told that they might lose some or all of the money, keep it (break even), or even increase it. The subjects then played a game similar to the "wheel-of-fortune" game found in most casinos. The trials were divided into two phases — expectancy and outcome. During the expectancy phase, the subjects were shown how much money they might win depending upon where the arrow stopped on a spinning disk. During the outcome phase, the arrow stopped on a designated monetary value, and the subjects found out whether they had won or lost money on that spin.

Data produced while the players watched the spinner showed:

  • The incentive of money produced blood flow changes in the brain similar to those seen in response to other forms of rewards, such as euphoria-producing drugs;
  • Blood flow in three areas of the brain rich in dopamine receptors, the NAc, SLEA, and hypothalamus, roughly paralleled findings in monkeys during anticipation and experience of reward; 
  • The right side of the brain responded predominantly to winning or the prospect of winning, while the left side of the brain responded to losing.

According to the researchers, the response patterns observed suggested that dysfunction of neural mechanisms and psychological processes crucial to decision-making and behavior may contribute to a broad range of impulse disorders such as drug abuse and compulsive gambling.

"Identifying these regions of the brain and mapping the neural pathways that process the anticipation and 'rewards' associated with drug abuse would be a tremendous boost to the development of medications or interventions that could block these circuits and provide other treatment approaches," stated Dr. Alan I. Leshner, director of The National Institute on Drug Abuse (NIDA).

The study on neural response to the incentive of money relates closely to other research now being conducted by NIDA that may lead to the development of new medications capable of blocking the brain's addictive reward response to cocaine. [See: New Drugs Could Prevent Cocaine's High, from your About Guide.]

(Personal Observation to NIH: The brain of a gambler on a winning streak will never, repeat never, be stimulated to go stand in the buffet line.)

 

Subscribe to the Newsletter
Name
Email

About.com Special Features

What is a Recession?

Sure, we're all talking about it, but what, exactly, defines a recession? More >

Weird Breaking News

A daily look at some of the oddest (and dumbest) crimes around. More >